The concept of 2226 is to provide a building with a comfortable range of interior temperatures (22oC to 26oC) without any heating, air conditioning or mechanical ventilation. The temperature range is guaranteed by a combination of thermal mass and natural ventilation, using the heat emitted from the bodies of the users and the office devices as energy sources. The concept has been applied to buildings in different locations and has since become a standalone research and development program within the Baumschlager Eberle practice, but here the focus is on the first example building of the series, built in Lustenau.

The GC Prostho Museum Research Centre is a research facility for a renowned dental health company, GC, that develops dental prostheses. The building functions as a laboratory and office space for 40 personnel but also has an exhibition space on the ground floor for the public. The project is known for its unique wooden structure that originates from the system of Cidori, an old Japanese toy.

The Gando Primary School was built to expand the sparse network of schools in the province of Boulgou, in the east of Burkina Faso, and addressed two characteristic problems of many educational buildings in the area: poor lighting and ventilation. In order to achieve sustainability, the project was based on the principles of designing for climatic comfort with low-cost construction, making the most of local materials and the potential of the local community, and adapting technology from the industrialized world in a simple way. Underlying the project was a strong didactic component: it was designed as an exemplar that would raise awareness in the local community of the merits of traditional materials, updated with simple techniques that would need few new skills. The school building includes three volumes, each containing a classroom measuring 7 x 9 metres, connected by a single roof make up the basic structure of the building, and each one of them accommodates one classroom for fifty students.